| 1 | Youth in Revolt (The Weinstein Company) | $15,372,000 | $6,932,000 | $2,311,000 | Jan 08, 2010 |
| 2 | Leap Year (2010) (Universal) | $26,083,000 | $9,261,000 | $3,087,000 | Jan 08, 2010 |
| 3 | Daybreakers (Lionsgate) | $30,292,000 | $15,243,000 | $5,081,000 | Jan 08, 2010 |
| 4 | The Book of Eli (Warner Bros.) | $95,436,000 | $32,997,000 | $10,999,000 | Jan 15, 2010 |
| 5 | The Last Station (Sony Pictures Classics) | $6,660,000 | $74,000 | $25,000 | Jan 15, 2010 |
| 6 | The Spy Next Door (Lionsgate) | $24,462,000 | $9,788,000 | $3,263,000 | Jan 15, 2010 |
| 7 | Legion (Sony / Screen Gems) | $40,423,000 | $17,613,000 | $5,871,000 | Jan 22, 2010 |
| 8 | Extraordinary Measures (CBS Films) | $12,562,000 | $6,051,000 | $2,017,000 | Jan 22, 2010 |
| 9 | The Tooth Fairy (Fox) | $60,403,000 | $14,099,000 | $4,700,000 | Jan 22, 2010 |
| 10 | Edge of Darkness (Warner Bros.) | $43,588,000 | $17,323,000 | $5,774,000 | Jan 29, 2010 |
| 11 | When in Rome (Disney) | $32,876,000 | $12,428,000 | $4,143,000 | Jan 29, 2010 |
| 12 | From Paris with Love (Lionsgate) | $24,230,000 | $8,211,000 | $2,737,000 | Feb 05, 2010 |
| 13 | Dear John (Sony / Screen Gems) | $80,522,000 | $30,662,000 | $10,221,000 | Feb 05, 2010 |
| 14 | Percy Jackson and the Olympians: The Lightning Thief (Fox) | $89,324,000 | $31,434,000 | $10,478,000 | Feb 12, 2010 |
| 15 | The Wolfman (Universal) | $62,372,000 | $31,679,000 | $10,560,000 | Feb 12, 2010 |
| 16 | Valentine's Day (Warner Bros. / New Line) | $111,186,000 | $56,617,000 | $18,872,000 | Feb 12, 2010 |
| 17 | Shutter Island (Paramount) | $128,824,000 | $41,323,000 | $13,774,000 | Feb 19, 2010 |
| 18 | The Ghost Writer (Summit) | $15,640,000 | $184,000 | $61,000 | Feb 19, 2010 |
| 19 | Cop Out (Warner Bros.) | $45,159,000 | $18,327,000 | $6,109,000 | Feb 26, 2010 |
| 20 | The Crazies (Overture) | $39,372,000 | $16,169,000 | $5,390,000 | Feb 26, 2010 |
| 21 | Brooklyn's Finest (Overture) | $27,336,000 | $13,435,000 | $4,478,000 | Mar 05, 2010 |
| 22 | Alice in Wonderland (2010) (Disney) | $336,309,000 | $116,837,000 | $38,946,000 | Mar 05, 2010 |
| 23 | Remember Me (Summit) | $19,189,000 | $8,140,000 | $2,713,000 | Mar 12, 2010 |
| 24 | Our Family Wedding (Fox Searchlight) | $20,378,000 | $7,678,000 | $2,559,000 | Mar 12, 2010 |
| 25 | Green Zone (Universal) | $35,276,000 | $14,400,000 | $4,800,000 | Mar 12, 2010 |
| 26 | She's Out of My League (Paramount) | $31,829,000 | $9,837,000 | $3,279,000 | Mar 12, 2010 |
| 27 | City Island (Anchor Bay) | $6,713,000 | $32,000 | $11,000 | Mar 19, 2010 |
| 28 | The Girl with the Dragon Tattoo (2009) (Music Box) | $10,159,000 | $338,000 | $113,000 | Mar 19, 2010 |
| 29 | The Bounty Hunter (Sony / Columbia) | $67,486,000 | $20,818,000 | $6,939,000 | Mar 19, 2010 |
| 30 | Hubble 3D (Warner Bros. / IMAX) | $38,440,000 | $414,000 | $138,000 | Mar 19, 2010 |
| 31 | Diary of a Wimpy Kid (Fox) | $64,409,000 | $22,266,000 | $7,422,000 | Mar 19, 2010 |
| 32 | Repo Men (Universal) | $13,882,000 | $6,165,000 | $2,055,000 | Mar 19, 2010 |
| 33 | How to Train Your Dragon (Paramount / DreamWorks) | $218,960,000 | $44,009,000 | $14,670,000 | Mar 26, 2010 |
| 34 | Hot Tub Time Machine (MGM) | $50,607,000 | $14,109,000 | $4,703,000 | Mar 26, 2010 |
| 35 | The Last Song (Disney) | $63,349,000 | $16,109,000 | $5,370,000 | Mar 31, 2010 |
| 36 | Clash of the Titans (2010) (Warner Bros.) | $164,249,000 | $61,623,000 | $20,541,000 | Apr 02, 2010 |
| 37 | Tyler Perry's Why Did I Get Married Too? (Lionsgate) | $60,477,000 | $29,475,000 | $9,825,000 | Apr 02, 2010 |
| 38 | Date Night (Fox) | $99,337,000 | $25,367,000 | $8,456,000 | Apr 09, 2010 |
| 39 | The Secret in Their Eyes (El Secreto de Sus Ojos) (Sony Pictures Classics) | $6,432,000 | $169,000 | $56,000 | Apr 16, 2010 |
| 40 | Kick-Ass (Lionsgate) | $48,376,000 | $19,954,000 | $6,651,000 | Apr 16, 2010 |
| 41 | Death at a Funeral (2010) (Sony / Screen Gems) | $43,010,000 | $16,320,000 | $5,440,000 | Apr 16, 2010 |
| 42 | Oceans (Disneynature) | $19,545,000 | $6,097,000 | $2,032,000 | Apr 22, 2010 |
| 43 | The Losers (Warner Bros.) | $23,741,000 | $9,466,000 | $3,155,000 | Apr 23, 2010 |
| 44 | The Back-up Plan (CBS Films) | $37,728,000 | $12,279,000 | $4,093,000 | Apr 23, 2010 |
| 45 | Furry Vengeance (Summit) | $17,742,000 | $6,670,000 | $2,223,000 | Apr 30, 2010 |
| 46 | A Nightmare on Elm Street (2010) (Warner Bros. / New Line) | $63,475,000 | $33,111,000 | $11,037,000 | Apr 30, 2010 |
| 47 | Iron Man 2 (Paramount) | $314,106,000 | $128,934,000 | $42,978,000 | May 07, 2010 |
| 48 | Babies (Focus) | $7,367,000 | $2,175,000 | $725,000 | May 07, 2010 |
| 49 | Letters to Juliet (Summit) | $53,369,000 | $13,626,000 | $4,542,000 | May 14, 2010 |
| 50 | Just Wright (Fox Searchlight) | $21,660,000 | $8,337,000 | $2,779,000 | May 14, 2010 |
| 51 | Robin Hood (Universal) | $105,937,000 | $36,292,000 | $12,097,000 | May 14, 2010 |
| 52 | Shrek Forever After (Paramount / DreamWorks) | $239,907,000 | $71,287,000 | $23,762,000 | May 21, 2010 |
| 53 | MacGruber (Universal / Rogue) | $8,580,000 | $4,069,000 | $1,356,000 | May 21, 2010 |
| 54 | Sex and the City 2 (Warner Bros. / New Line) | $95,952,000 | $31,198,000 | $10,399,000 | May 27, 2010 |
| 55 | Prince of Persia: The Sands of Time (Disney) | $91,335,000 | $30,286,000 | $10,095,000 | May 28, 2010 |
| 56 | Splice (Warner Bros) | $17,118,000 | $7,432,000 | $2,477,000 | Jun 04, 2010 |
| 57 | Marmaduke (Fox) | $33,858,000 | $11,673,000 | $3,891,000 | Jun 04, 2010 |
| 58 | Killers (Lionsgate) | $47,358,000 | $15,938,000 | $5,313,000 | Jun 04, 2010 |
| 59 | Get Him to the Greek (Universal) | $61,361,000 | $17,682,000 | $5,894,000 | Jun 04, 2010 |
| 60 | The A-Team (Fox) | $77,711,000 | $25,832,000 | $8,611,000 | Jun 11, 2010 |
| 61 | The Karate Kid (2010) (Sony / Columbia) | $177,711,000 | $56,019,000 | $18,673,000 | Jun 11, 2010 |
| 62 | Winter's Bone (Roadside Attractions) | $6,573,000 | $85,000 | $28,000 | Jun 11, 2010 |
| 63 | Cyrus (Fox Searchlight) | $7,503,000 | $183,000 | $61,000 | Jun 18, 2010 |
| 64 | Jonah Hex (Warner Bros.) | $10,614,000 | $5,413,000 | $1,804,000 | Jun 18, 2010 |
| 65 | Toy Story 3 (Disney) | $417,635,000 | $111,006,000 | $37,002,000 | Jun 18, 2010 |
| 66 | I Am Love (Magnolia) | $5,037,000 | $122,000 | $41,000 | Jun 18, 2010 |
| 67 | Knight and Day (Fox) | $76,907,000 | $20,268,000 | $6,756,000 | Jun 23, 2010 |
| 68 | Grown Ups (Sony / Columbia) | $163,028,000 | $40,763,000 | $13,588,000 | Jun 25, 2010 |
| 69 | The Twilight Saga: Eclipse (Summit) | $302,436,000 | $65,243,000 | $21,748,000 | Jun 30, 2010 |
| 70 | The Last Airbender (Paramount) | $132,435,000 | $40,581,000 | $13,527,000 | Jul 01, 2010 |
| 71 | Despicable Me (Universal) | $253,108,000 | $56,755,000 | $18,918,000 | Jul 09, 2010 |
| 72 | The Girl Who Played With Fire (Music Box) | $7,687,000 | $911,000 | $304,000 | Jul 09, 2010 |
| 73 | The Kids Are All Right (Focus) | $20,943,000 | $495,000 | $165,000 | Jul 09, 2010 |
| 74 | Predators (Fox) | $52,330,000 | $24,918,000 | $8,306,000 | Jul 09, 2010 |
| 75 | The Sorcerer's Apprentice (Disney) | $63,551,000 | $17,731,000 | $5,910,000 | Jul 14, 2010 |
| 76 | Inception (Warner Bros.) | $294,430,000 | $63,183,000 | $21,061,000 | Jul 16, 2010 |
| 77 | Salt (Sony / Columbia) | $119,061,000 | $36,239,000 | $12,080,000 | Jul 23, 2010 |
| 78 | Ramona and Beezus (Fox) | $26,333,000 | $7,860,000 | $2,620,000 | Jul 23, 2010 |
| 79 | Get Low (Sony Pictures Classics) | $9,235,000 | $89,000 | $30,000 | Jul 30, 2010 |
| 80 | Dinner for Schmucks (Paramount / DreamWorks) | $73,489,000 | $23,677,000 | $7,892,000 | Jul 30, 2010 |
| 81 | Charlie St. Cloud (Universal) | $31,360,000 | $12,460,000 | $4,153,000 | Jul 30, 2010 |
| 82 | Cats & Dogs: The Revenge of Kitty Galore (Warner Bros.) | $43,862,000 | $12,357,000 | $4,119,000 | Jul 30, 2010 |
| 83 | Step Up 3D (Disney) | $42,669,000 | $15,913,000 | $5,304,000 | Aug 06, 2010 |
| 84 | The Other Guys (Sony / Columbia) | $119,975,000 | $35,768,000 | $11,923,000 | Aug 06, 2010 |
| 85 | Eat Pray Love (Sony / Columbia) | $81,085,000 | $23,251,000 | $7,750,000 | Aug 13, 2010 |
| 86 | Scott Pilgrim vs. the World (Universal) | $31,724,000 | $10,677,000 | $3,559,000 | Aug 13, 2010 |
| 87 | The Expendables (Lionsgate) | $103,722,000 | $35,046,000 | $11,682,000 | Aug 13, 2010 |
| 88 | Vampires Suck (Fox) | $36,894,000 | $12,280,000 | $4,093,000 | Aug 18, 2010 |
| 89 | Lottery Ticket (Warner Bros.) | $24,877,000 | $10,720,000 | $3,573,000 | Aug 20, 2010 |
| 90 | Nanny McPhee Returns (Universal) | $29,195,000 | $8,461,000 | $2,820,000 | Aug 20, 2010 |
| 91 | Piranha 3D (Weinstein Company) | $25,162,000 | $10,171,000 | $3,390,000 | Aug 20, 2010 |
| 92 | The Switch (2010) (Miramax) | $27,955,000 | $8,490,000 | $2,830,000 | Aug 20, 2010 |
| 93 | Takers (Sony / Screen Gems) | $58,111,000 | $20,642,000 | $6,881,000 | Aug 27, 2010 |
| 94 | The Last Exorcism (Lionsgate) | $41,294,000 | $20,496,000 | $6,832,000 | Aug 27, 2010 |
| 95 | The American (Focus) | $35,832,000 | $13,261,000 | $4,420,000 | Sep 01, 2010 |
| 96 | Machete (Fox) | $26,762,000 | $11,489,000 | $3,830,000 | Sep 03, 2010 |
| 97 | Going the Distance (2010) (Warner Bros. / New Line) | $17,917,000 | $6,929,000 | $2,310,000 | Sep 03, 2010 |
| 98 | Resident Evil: Afterlife (Sony / Screen Gems) | $60,510,000 | $26,819,000 | $8,940,000 | Sep 10, 2010 |
| 99 | Easy A (Sony / Screen Gems) | $58,772,000 | $17,846,000 | $5,949,000 | Sep 17, 2010 |
| 100 | Devil (Universal) | $33,814,000 | $12,367,000 | $4,122,000 | Sep 17, 2010 |
| 101 | The Town (Warner Bros.) | $92,770,000 | $23,959,000 | $7,986,000 | Sep 17, 2010 |
| 102 | Alpha and Omega (Lionsgate) | $25,266,000 | $9,165,000 | $3,055,000 | Sep 17, 2010 |
| 103 | You Again (Disney) | $25,865,000 | $8,461,000 | $2,820,000 | Sep 24, 2010 |
| 104 | Wall Street: Money Never Sleeps (Fox) | $52,807,000 | $19,132,000 | $6,377,000 | Sep 24, 2010 |
| 105 | Legend of the Guardians: The Owls of Ga'Hoole (Warner Bros.) | $56,028,000 | $16,214,000 | $5,405,000 | Sep 24, 2010 |
| 106 | Waiting for 'Superman' (Paramount Vantage) | $6,458,000 | $140,000 | $47,000 | Sep 24, 2010 |
| 107 | Case 39 (Paramount Vantage) | $13,346,000 | $5,384,000 | $1,795,000 | Oct 01, 2010 |
| 108 | Let Me In (Relativity / Overture) | $12,212,000 | $5,180,000 | $1,727,000 | Oct 01, 2010 |
| 109 | The Social Network (Sony / Columbia) | $97,577,000 | $22,588,000 | $7,529,000 | Oct 01, 2010 |
| 110 | Life As We Know It (Warner Bros.) | $53,713,000 | $14,598,000 | $4,866,000 | Oct 08, 2010 |
| 111 | My Soul to Take (Universal / Rogue) | $14,838,000 | $6,886,000 | $2,295,000 | Oct 08, 2010 |
| 112 | Secretariat (Disney) | $60,092,000 | $12,775,000 | $4,258,000 | Oct 08, 2010 |
| 113 | It's Kind of a Funny Story (Focus) | $6,404,000 | $2,026,000 | $675,000 | Oct 08, 2010 |
| 114 | Hereafter (Warner Bros.) | $32,954,000 | $222,000 | $74,000 | Oct 15, 2010 |
| 115 | Jackass 3D (Paramount) | $117,973,000 | $50,673,000 | $16,891,000 | Oct 15, 2010 |
| 116 | Conviction (Fox Searchlight) | $6,826,000 | $103,000 | $34,000 | Oct 15, 2010 |
| 117 | Red (2010) (Summit) | $90,953,000 | $21,899,000 | $7,300,000 | Oct 15, 2010 |
| 118 | Paranormal Activity 2 (Paramount) | $85,290,000 | $40,936,000 | $13,645,000 | Oct 22, 2010 |
| 119 | The Girl Who Kicked the Hornet's Nest (Music Box) | $5,222,000 | $728,000 | $243,000 | Oct 29, 2010 |
| 120 | Saw 3D (Lionsgate) | $46,000,000 | $24,384,000 | $8,128,000 | Oct 29, 2010 |
| 121 | Due Date (Warner Bros.) | $101,176,000 | $32,897,000 | $10,966,000 | Nov 05, 2010 |
| 122 | For Colored Girls (Lionsgate) | $37,969,000 | $19,621,000 | $6,540,000 | Nov 05, 2010 |
| 123 | Fair Game (2010) (Summit) | $9,601,000 | $655,000 | $218,000 | Nov 05, 2010 |
| 124 | Megamind (Paramount / DreamWorks) | $149,356,000 | $46,308,000 | $15,436,000 | Nov 05, 2010 |
| 125 | 127 Hours (Fox Searchlight) | $18,451,000 | $267,000 | $89,000 | Nov 05, 2010 |
| 126 | Morning Glory (2010) (Paramount) | $31,208,000 | $9,262,000 | $3,087,000 | Nov 10, 2010 |
| 127 | Unstoppable (2010) (Fox) | $82,080,000 | $22,832,000 | $7,611,000 | Nov 12, 2010 |
| 128 | Skyline (Universal / Rogue) | $21,529,000 | $11,767,000 | $3,922,000 | Nov 12, 2010 |
| 129 | The Next Three Days (Lionsgate) | $21,283,000 | $6,584,000 | $2,195,000 | Nov 19, 2010 |
| 130 | Harry Potter and the Deathly Hallows: Part 1 (Warner Bros.) | $297,859,000 | $125,810,000 | $41,937,000 | Nov 19, 2010 |
| 131 | Love and Other Drugs (Fox) | $32,572,000 | $9,801,000 | $3,267,000 | Nov 24, 2010 |
| 132 | Faster (2010) (CBS Films) | $23,387,000 | $8,577,000 | $2,859,000 | Nov 24, 2010 |
| 133 | Burlesque (Sony / Screen Gems) | $39,691,000 | $12,023,000 | $4,008,000 | Nov 24, 2010 |
| 134 | Tangled (Disney) | $202,095,000 | $49,076,000 | $16,359,000 | Nov 24, 2010 |
| 135 | The King's Speech (Weinstein Company) | $139,677,000 | $358,000 | $119,000 | Nov 26, 2010 |
| 136 | Black Swan (Fox Searchlight) | $107,632,000 | $1,453,000 | $484,000 | Dec 03, 2010 |
| 137 | The Warrior's Way (Relativity Media) | $5,693,000 | $3,068,000 | $1,023,000 | Dec 03, 2010 |
| 138 | The Chronicles of Narnia: The Voyage of the Dawn Treader (Fox) | $105,048,000 | $24,157,000 | $8,052,000 | Dec 10, 2010 |
| 139 | The Tourist (Sony / Columbia) | $68,060,000 | $16,577,000 | $5,526,000 | Dec 10, 2010 |
| 140 | The Fighter (Paramount) | $94,210,000 | $302,000 | $101,000 | Dec 10, 2010 |
| 141 | Yogi Bear (Warner Bros.) | $100,881,000 | $16,515,000 | $5,505,000 | Dec 17, 2010 |
| 142 | How Do You Know (Sony / Columbia) | $30,404,000 | $7,532,000 | $2,511,000 | Dec 17, 2010 |
| 143 | TRON: Legacy (Disney) | $173,153,000 | $44,305,000 | $14,768,000 | Dec 17, 2010 |
| 144 | Little Fockers (Universal) | $149,379,000 | $31,029,000 | $10,343,000 | Dec 22, 2010 |
| 145 | True Grit (2010) (Paramount) | $172,134,000 | $24,988,000 | $8,329,000 | Dec 22, 2010 |
| 146 | Country Strong (Sony / Screen Gems) | $20,347,000 | $31,000 | $10,000 | Dec 22, 2010 |
| 147 | Gulliver's Travels (2010) (Fox) | $43,050,000 | $6,348,000 | $2,116,000 | Dec 25, 2010 |
| 148 | Biutiful (Roadside Attractions) | $5,134,000 | $46,000 | $15,000 | Dec 29, 2010 |
| 149 | Blue Valentine (2010) (Weinstein Company) | $9,768,000 | $195,000 | $65,000 | Dec 29, 2010 |
